| Item |
Information |
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Drug Groups
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approved |
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Description
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Proparacaine is a topical anesthetic drug of the amino ester group. It is available as its hydrochloride salt in ophthalmic solutions at a concentration of 0.5%. [Wikipedia] |
| Indication |
Used as a local (ophthalmic) anesthetic. |
| Pharmacology |
Proparacaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. More specifically, proparacaine appears to bind or antagonize the function of voltage gated sodium channels. |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Biotransformation |
Plasma |
| External Links |
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