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Tymazoline

产品号 DB08803 公司名称 DrugBank
CAS号 24243-97-8 公司网站 http://www.ualberta.ca/
分子式 C14H20N2O 电 话 (780) 492-3111
分子量 232.3214 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 6403

产品价格信息

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产品别名

标题
Tymazoline
IUPAC标准名
2-[5-methyl-2-(propan-2-yl)phenoxymethyl]-4,5-dihydro-1H-imidazole
IUPAC传统名
tymazoline
商标名
Thymazen
别名
Pernazene

产品登记号

CAS号 24243-97-8

产品性质

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description Tymazoline is a nasal preparation.
Indication For the treatment of Inflammation of the lining of the nose and paranasal sinuses and allergic inflammation of nasopharyngeal.
Pharmacology Tymazoline is a drug with antihistaminic and sympathomimetic properties. It locally reduces swelling, inflammation and mucosal secretions of the nasal passages.
Toxicity A large overdose or accidental oral intake, especially in children, may cause excessive sedation with drowsiness, reduced body temperature, heart rate relief and fluctuations in blood pressure and collapse.
References
• Levrier J, Molon-Noblot S, Duval D, Lloyd KG: A new ex vivo method for the study of nasal drops on ciliary function. Fundam Clin Pharmacol. 1989;3(5):471-82. [Pubmed]
• Lorino AM, Lofaso F, Drogou I, Abi-Nader F, Dahan E, Coste A, Lorino H: Effects of different mechanical treatments on nasal resistance assessed by rhinometry. Chest. 1998 Jul;114(1):166-70. [Pubmed]
External Links
• Wikipedia

参考文献

  • Levrier J, Molon-Noblot S, Duval D, Lloyd KG: A new ex vivo method for the study of nasal drops on ciliary function. Fundam Clin Pharmacol. 1989;3(5):471-82. Pubmed
  • Lorino AM, Lofaso F, Drogou I, Abi-Nader F, Dahan E, Coste A, Lorino H: Effects of different mechanical treatments on nasal resistance assessed by rhinometry. Chest. 1998 Jul;114(1):166-70. Pubmed