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Tymazoline

产品号 DB08803 公司名称 DrugBank
CAS号 24243-97-8 公司网站 http://www.ualberta.ca/
分子式 C14H20N2O 电 话 (780) 492-3111
分子量 232.3214 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 6403

产品价格信息

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产品别名

标题
Tymazoline
IUPAC标准名
2-[5-methyl-2-(propan-2-yl)phenoxymethyl]-4,5-dihydro-1H-imidazole
IUPAC传统名
tymazoline
商标名
Thymazen
别名
Pernazene

产品登记号

CAS号 24243-97-8

产品性质

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description Tymazoline is a nasal preparation.
Indication For the treatment of Inflammation of the lining of the nose and paranasal sinuses and allergic inflammation of nasopharyngeal.
Pharmacology Tymazoline is a drug with antihistaminic and sympathomimetic properties. It locally reduces swelling, inflammation and mucosal secretions of the nasal passages.
Toxicity A large overdose or accidental oral intake, especially in children, may cause excessive sedation with drowsiness, reduced body temperature, heart rate relief and fluctuations in blood pressure and collapse.
References
Levrier J, Molon-Noblot S, Duval D, Lloyd KG: A new ex vivo method for the study of nasal drops on ciliary function. Fundam Clin Pharmacol. 1989;3(5):471-82. [Pubmed]
Lorino AM, Lofaso F, Drogou I, Abi-Nader F, Dahan E, Coste A, Lorino H: Effects of different mechanical treatments on nasal resistance assessed by rhinometry. Chest. 1998 Jul;114(1):166-70. [Pubmed]
External Links
Wikipedia

参考文献

  • Levrier J, Molon-Noblot S, Duval D, Lloyd KG: A new ex vivo method for the study of nasal drops on ciliary function. Fundam Clin Pharmacol. 1989;3(5):471-82. Pubmed
  • Lorino AM, Lofaso F, Drogou I, Abi-Nader F, Dahan E, Coste A, Lorino H: Effects of different mechanical treatments on nasal resistance assessed by rhinometry. Chest. 1998 Jul;114(1):166-70. Pubmed