| Item |
Information |
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Drug Groups
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approved |
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Description
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Isothipendyl is an antihistamine and anticholinergic used as an antipruritic. |
| Indication |
For the topical treatment of itching associated with allergic reactions. |
| Pharmacology |
Isothipendyl, an azaphenothiazine derivative, competitively binds to histamine (H1) receptors, resulting in inhibition of the pharmacological effects of histamines. It also has some sedative, anticholinergic and antiserotoninergic effects. |
| Affected Organisms |
| • |
Humans and other mammals |
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| References |
| • |
Moreau A, Dompmartin A, Dubreuil A, Leroy D: Phototoxic and photoprotective effects of topical isothipendyl. Photodermatol Photoimmunol Photomed. 1995 Apr;11(2):50-4.
[Pubmed]
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