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Isoflurane

产品号 DB00753 公司名称 DrugBank
CAS号 26675-46-7 公司网站 http://www.ualberta.ca/
分子式 C3H2ClF5O 电 话 (780) 492-3111
分子量 184.492396 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 633

产品价格信息

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产品别名

标题
Isoflurane
IUPAC标准名
2-chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
IUPAC传统名
isoflurane
商标名
Aerrane
Isoflurane [Usan:Ban:Inn:Jan]
Forene
Ethane
Forane
Isofluranum [INN-Latin]

产品登记号

PubChem CID 3763
CAS号 26675-46-7
PubChem SID 46505880

产品性质

疏水性(logP) 2.1
溶解度 Insoluble

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description A stable, non-explosive inhalation anesthetic, relatively free from significant side effects. [PubChem]
Indication For induction and maintenance of general anesthesia.
Pharmacology Isoflurane is a general inhalation anesthetic used for induction and maintenance of general anesthesia. It induces muscle relaxation and reduces pains sensitivity by altering tissue excitability. It does so by decreasing the extent of gap junction mediated cell-cell coupling and altering the activity of the channels that underlie the action potential.
Toxicity LC50=15300 ppm/3 hrs (inhalation by rat)
Affected Organisms
Humans and other mammals
Biotransformation Minimal
External Links
Wikipedia
RxList

参考文献