| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
A synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception. [PubChem] |
| Indication |
For use as an oral contraceptive in the prevention of pregnancy. |
| Pharmacology |
Norethindrone is a synthetic oral progestin. It is used for contraception or to treat such conditions as secondary amenorrhea, abnormal uterine bleeding, and endometriosis. As an oral contraceptive, norethindrone is available as either a single agent or in combination with an estrogen. |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Biotransformation |
Hepatic |
| Absorption |
Absolute oral bioavailability approximately 64% |
| Half Life |
7 hours |
| Protein Binding |
>95% |
| External Links |
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