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Pirenzepine

产品号 DB00670 公司名称 DrugBank
CAS号 28797-61-7 公司网站 http://www.ualberta.ca/
分子式 C19H21N5O2 电 话 (780) 492-3111
分子量 351.40234 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 552

产品价格信息

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产品别名

标题
Pirenzepine
IUPAC标准名
2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
IUPAC传统名
pirenzepine
商标名
Pirenzepin
Pirenzepinum [INN-Latin]
Tabe
Pirenzepine Gastrozepin
Bisvanil
Gasteril
Gastrozepin
Leblon
Pirenzepina [INN-Spanish]
Ulcosan

产品登记号

CAS号 28797-61-7
PubChem SID 46509029
PubChem CID 4848

产品性质

疏水性(logP) 0.6

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as cimetidine and ranitidine. It is generally well tolerated by patients. [PubChem]
Indication For the treatment of peptic ulcer, gastric ulcer, and duodenal ulcer.
Pharmacology Pirenzepine belongs to a group of medications called antispasmodics/anticholinergics. These medications are used to relieve cramps or spasms of the stomach, intestines, and bladder. Pirenzepine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be used to prevent nausea, vomiting, and motion sickness.
Affected Organisms
Humans and other mammals
References
Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. [Pubmed]
External Links
Wikipedia

参考文献

  • Czepita D: [Fundamentals of modern treatment of myopia] Ann Acad Med Stetin. 2005;51(2):5-9. Pubmed