Triamcinolone

• 产品号: DB00620
• CAS号: 124-94-7
• 分子式: C21H27FO6
• 分子量: 394.4338832

产品别名

• 标题: Triamcinolone
• IUPAC标准名: (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one
• IUPAC传统名: triamcinolone
• 商标名: Sk-Triamcinolone; Triamcet; Adcortyl; Trilone; Kenacort-A; Polcortolon; Delphicort; Kenacort; Kenacort-Ag; Kenalog; Ledercort; Nasacort Hfa; Oracort; Tri-Nasal; Triacort; Triamcinolon; Triatex; Fougera; Aristocort Tablets; Aristogel; Aristospan; Celeste; Cinolone-T; Kenalog in Orabase; Kenalog-10; Nasacort; Omcilon; Omicilon; Oralone; Orion; Rodinolone; Triam-Tablinen; Triamcinlon; Vetalog; Tristoject; Aristocort; Aristocort A; Azmacort; Cinolone; Flutex; Kenalog-40; Kenalog-H; Nasacort Aq; Triacet; Tricortale; Triderm; Trymex; Volon; Volon A
• 别名: Triamcinolone acetonide; Fluoxyprednisolone; Tiamcinolonum [INN-Latin]; Triamcinalone; Triamcinolona [INN-Spanish]; Triamcinolonum [INN]; Triamcinolone diacetate; Triamcinolone hexacetonide; Fluoxiprednisolone

产品登记号

• CAS号: 124-94-7
• PubChem CID: 31307
• PubChem SID: 46507950

产品性质

• 疏水性(logP): 0.2
• 溶解度: 80 mg/L

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: A glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. (From Martindale, The Extra Pharmacopoeia, 30th ed, p739)
• Indication: For the treatment of perennial and seasonal allergic rhinitis.
• Pharmacology: Triamcinolone and its derivatives are synthetic glucocorticoids that are used for their antiinflammatory or immunosuppressive properties.
• Toxicity: LD₅₀=>500mg/kg (in rats)
• Affected Organisms: Humans and other mammals
• Biotransformation: Hepatic.
• Absorption: Rapid absorption following oral administration
• Half Life: 88 minutes
• Protein Binding: 68%
• External Links: Wikipedia; RxList; PDRhealth; Drugs.com