您当前所在的位置:首页 > 产品中心 > 产品信息
Candoxatril_分子结构_CAS_118785-03-8)
点击图片或这里关闭

Candoxatril

产品号 DB00616 公司名称 DrugBank
CAS号 118785-03-8 公司网站 http://www.ualberta.ca/
分子式 C29H41NO7 电 话 (780) 492-3111
分子量 515.63834 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 498

产品价格信息

请登录

产品别名

标题
Candoxatril
IUPAC标准名
4-{1-[(2S)-3-(2,3-dihydro-1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid
IUPAC传统名
4-{1-[(2S)-3-(2,3-dihydro-1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl]cyclopentaneamido}cyclohexane-1-carboxylic acid
商标名
Candoxatrilat

产品登记号

CAS号 118785-03-8

产品性质

疏水性(logP) 3.7

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), the active enantiomer of candoxatrilat (UK-69578), a potent neutral endopeptidase (NEP) inhibitor used in the treatment of chronic heart failure.
Indication For treatment of hypertension, improve exercise capacity in patients with CHF receiving angiotensin converting enzyme inhibition.
Pharmacology Candoxatril is the orally-active prodrug of candoxatrilat (UK-73967), the active enantiomer of candoxatrilat (UK-69578), a potent neutral endopeptidase (NEP) inhibitor used in the treatment of chronic heart failure in man.
Affected Organisms
Humans and other mammals

参考文献