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Monobenzone

产品号 DB00600 公司名称 DrugBank
CAS号 103-16-2 公司网站 http://www.ualberta.ca/
分子式 C13H12O2 电 话 (780) 492-3111
分子量 200.23318 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 482

产品价格信息

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产品别名

标题
Monobenzone
IUPAC标准名
4-(benzyloxy)phenol
IUPAC传统名
monobenzone
商标名
Carmifal
Agerite
Alba
Alba-Dome
Depigman
Dermochinona
Leucodinine
Monobenzon
Pigmex
Superlite
AgeRite Alba
Benoquin
别名
Hydroquinone benzyl ether
p-Hydroxyphenyl benzyl ether
Benzoquin
Monobenzyl ether hydroquinone
Monobenzyl hydroquinone
Hydrochinon monobenzylether [Czech]
Hydroquinone monobenzyl ether
Benzyl p-hydroxyphenyl ether
Benzyl hydroquinone
Monobenzona [INN-Spanish]
Monobenzone [INN]
Monobenzonum [INN-Latin]
Monobenzyl Ether of Hydroquinone

产品登记号

CAS号 103-16-2
PubChem SID 46507466
PubChem CID 7638

产品性质

疏水性(logP) 3.2
溶解度 251 mg/L

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water.

The topical application of monobenzone in animals increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation.
Indication Used topically to treat the loss of skin color (vitiligo).
Pharmacology Monobenzone is the monobenzyl ether of hydroquinone. Monobenzone, applied topically to the skin, is used as a depigmenting agent inhibitting melanin produced by polymerization of oxidation products of tyrosine and dihydroxyphenyl compounds. Monobenzone works by permanently removing color from normal skin located around skin with vitiligo.
Affected Organisms
Humans and other mammals
External Links
Wikipedia
Drugs.com

参考文献