Oxytetracycline

• 产品号: DB00595
• CAS号: 79-57-2
• 分子式: C22H24N2O9
• 分子量: 460.43396

产品别名

• 标题: Oxytetracycline
• IUPAC标准名: (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• IUPAC传统名: oxytetracycline
• 商标名: Oxytetracycline HCl; Terramycin; Oxytetracycline anhydrous

产品登记号

• PubChem SID: 46507025
• PubChem CID: 5280972
• CAS号: 79-57-2

产品性质

• 疏水性(logP): -1.3
• 溶解度: 0.6 mg/mL (6.9 mg/mL as HCl salt)

产品详细信息

详细说明 (English)

• Drug Groups: approved
• Description: A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions. [PubChem]
• Indication: Oxytetracycline is indicated for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae.
• Pharmacology: Oxytetracycline is known as a broad-spectrum antibiotic due to its activity against such a wide range of infections. It was the second of the tetracyclines to be discovered. Oxytetracycline, like other tetracyclines, is used to treat many infections common and rare. Its better absorption profile makes it preferable to tetracycline for moderately severe acne, but alternatives sould be sought if no improvement occurs by 3 months.
• Toxicity: Adverse effects may include stomach or bowel upsets and rarely allergic reactions. Very rarely severe headache and vision problems may be signs of dangerous intracranial hypertenion.
• Affected Organisms: Enteric bacteria and other eubacteria
• Absorption: Readily absorbed following oral administration.
• External Links: Wikipedia; RxList