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Cinalukast

产品号 DB00587 公司名称 DrugBank
CAS号 128312-51-6 公司网站 http://www.ualberta.ca/
分子式 C23H28N2O3S 电 话 (780) 492-3111
分子量 412.54502 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 469

产品价格信息

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产品别名

标题
Cinalukast
IUPAC标准名
3-({3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]phenyl}carbamoyl)-2,2-diethylpropanoic acid
IUPAC传统名
@cinalukast
商标名
Cinalukast [Usan:Inn]

产品登记号

PubChem SID 46505799
CAS号 128312-51-6
PubChem CID 6436135

产品性质

疏水性(logP) 4

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved
Description Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Indication For Protection against second- phase inflamation in exercise-induced bronchoconstriction and Asthma.
Pharmacology Used in the treatment of asthma, cinalukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Cinalukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Affected Organisms
Humans and other mammals

参考文献