| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
A direct-acting smooth muscle relaxant used to dilate blood vessels. It may cause gastrointestinal distress and tachycardia. Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries. |
| Indication |
Used in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps. |
| Pharmacology |
Cyclandelate is in a class of drugs called vasodilators. Cyclandelate relaxes veins and arteries, which makes them wider and allows blood to pass through them more easily. |
| Toxicity |
Acute oral toxicity (LD50): 3950 mg/kg [Guinea pig] |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Absorption |
Well absorbed following oral administration. |
| External Links |
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