Omeprazole

• 产品号: Bio-0888
• CAS号: 131959-78-9
• 分子式: C17H19N3O3S
• 分子量: 345.41606

产品别名

• 标题: Omeprazole
• IUPAC标准名: 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole
• IUPAC传统名: 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole
• 别名: Belmazol; Parizac; Mepral; Mopral; Gastroloc; Zoltum; Audazol; Logastric; Omapren; Omeprazen; Prilosec; Antra; Losec

产品登记号

• CAS号: 131959-78-9

产品性质

• 应用领域: Antiulcer agent
• 生物活性机理: Proton pump inhibitor
• 生物活性机理: Inhibits gastric acid secretion

参考文献

• Eur. Pat., 1979, Aktiebolag Haessle, 5 129; CA, 92, 198396z, (synth, pharmacol)
• Adams, M.H. et al., Clin. Pharm., 1988, 7, 725, (rev)
• Brndstrom, A. et al., Acta Chem. Scand., 1989, 43, 536; 549; 569; 577; 587; 595, (props, bibl)
• Ohishi, H. et al., Acta Cryst. C, 1989, 45, 1921, (cryst struct)
• Maton, P.N., N. Engl. J. Med., 1991, 324, 965, (rev)
• Hetzel, D.J., Digestion, Suppl. 1, 1992, 51, 35, (clin trials, rev)
• Ferner, R.E. et al., Human Exp. Toxicol., 1993, 12, 541, (tox, human)
• Massoomi, F. et al., Pharmacotherapy (Carlisle, Mass.), 1993, 13, 46, (rev)
• Yeomans, N.D., Adverse Drug React. Toxicol. Rev., 1994, 13, 145, (tox, rev)
• Creutzfeldt, W., Drug Saf., 1994, 10, 66, (rev)
• Wilde, M.I. et al., Drugs, 1994, 48, 91, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 5818, (synonyms)
• Unge, S. et al., Tetrahedron: Asymmetry, 1997, 8, 1967-1970, (bibl, resoln, abs config)
• Langtry, H.D. et al., Drugs, 1998, 56, 447-486, (rev)