Metergoline

• 产品号: Bio-0869
• CAS号: 17692-51-2
• 分子式: C25H29N3O2
• 分子量: 403.51666

产品别名

• 标题: Metergoline
• IUPAC标准名: benzyl N-{[(2R,4S,7R)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl}carbamate
• IUPAC传统名: benzyl N-{[(2R,4S,7R)-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0^2,^7.0^1^2,^1^6]hexadeca-1(16),9,12,14-tetraen-4-yl]methyl}carbamate
• 别名: Methergoline; Liserdol; Al-Migren

产品登记号

• CAS号: 17692-51-2

产品性质

• 应用领域: Analgesic
• 应用领域: Antipyretic
• 应用领域: Migraine disorgers therapy
• 生物活性机理: Dopamine agonist
• 生物活性机理: Serotonin receptor antagonist
• 生物活性机理: 5-HT2 antagonist
• 生物活性机理: 5-HT1 antagonist and 5-HT1D ligand
• 生物活性机理: Has moderate affinity for 5-HT6 and high affinity for 5-HT7

参考文献

• Bagdy et al (1992) Pharmacological characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists. Eur.J.Pharmacol. 210 285.