Bergapten

• 产品号: Bio-0829
• CAS号: 484-20-8
• 分子式: C12H8O4
• 分子量: 216.18952

产品别名

• 标题: Bergapten
• IUPAC标准名: 4-methoxy-7H-furo[3,2-g]chromen-7-one
• IUPAC传统名: 4-methoxy-7H-furo[3,2-g]chromen-7-one
• 别名: Majudin; Heraclin

产品登记号

• CAS号: 484-20-8

产品性质

• 应用领域: Antipsoriatic
• 应用领域: Antiinflammatory
• 应用领域: Antihistamine agent
• 应用领域: Show spasmolytic props
• 应用领域: Used in the treatment of vitiligo
• 生物来源: Major constit. of bergamot oil (Citrus bergamia), also from Heracleum giganteum and Ammi majus. Widely distributed in the Rutaceae and Umbelliferae
• 生物活性机理: Spasmolytic
• 生物活性机理: Radiosensitizer

参考文献

• Kawaii, S. et al., J. Agric. Food Chem., 1999, 47, 4073, (activity)
• Oliva, A. et al., J. Chem. Ecol., 1999, 25, 519-526, (activity)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, MFN275
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 2, 1321A, (nmr)
• Baetcke, E. et al., Ber., 1912, 45, 3705, (struct)
• Glatfelder, A. et al., Helv. Chim. Acta, 1920, 3, 541; 1921, 4, 718, (synth)
• Socias, L. et al., Ber., 1934, 67, 59, (isol)
• Kubiczek, G. et al., Ber., 1937, 70, 1253, (synth)
• Karrer, W. et al., Konstitution und Vorkommen der Organischen Pflanzenstoffe, 2nd edn., Birkhuser Verlag, Basel, 1972, no. 1369, (occur, deriv)
• Austin, D.J. et al., Phytochemistry, 1973, 12, 1657, (biosynth)
• Boyd, R.K. et al., Can. J. Chem., 1979, 57, 1995, (ms)
• Duddeck, H. et al., Phytochemistry, 1979, 18, 139, (cmr)
• IARC Monog., 1986, 40, 327, (tox, rev)
• Gu, Z. et al., Chem. Pharm. Bull., 1990, 38, 2498, (deriv)
• Ginderow, D., Acta Cryst. C, 1991, 47, 2144, (cryst struct)
• Diawara, M.M. et al., J. Agric. Food Chem., 1995, 43, 723-727, (occur)
• Masuda, T. et al., Phytochemistry, 1998, 47, 13-16, (Bergapten, isol, pmr, cmr)