Estradiol

• 产品号: Bio-0812
• CAS号: 50-28-2
• 分子式: C18H24O2
• 分子量: 272.38196

产品别名

• 标题: Estradiol
• IUPAC标准名: (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2(7),3,5-triene-5,14-diol
• IUPAC传统名: (1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2(7),3,5-triene-5,14-diol

产品登记号

• CAS号: 50-28-2

产品性质

• 应用领域: The most potent of the natural estrogens
• 应用领域: Estradiol (and its semisynthetic esters) are used in estrogen replacement therapy
• 生物来源: Isol. from ovaries and pregnancy urine. Sex pheromone for mallard ducks
• 生物活性机理: Estradiol enters cells freely and interacts with a cytoplasmic target cell receptor.
• 生物活性机理: When the estrogen receptor has bound its ligand it can enter the nucleus of the target cell, and regulate gene transcription which leads to formation of messenger RNA.
• 生物活性机理: The mRNA interacts with ribosomes to produce specific proteins that express the effect of estradiol upon the target cell.

参考文献

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