您当前所在的位置:首页 > 产品中心 > 产品信息
Fluphenazine_分子结构_CAS_69-23-8)
点击图片或这里关闭

Fluphenazine

产品号 Bio-0775 公司名称 InterBioScreen
CAS号 69-23-8 公司网站 http://www.ibscreen.com
分子式 C22H26F3N3OS 电 话 +7 49652 40091
分子量 437.5215496 传 真 +7 49652 40092
纯 度 电子邮件 screen@ibscreen.chg.ru
保 存 Chembase数据库ID: 505

产品价格信息

请登录

产品别名

标题
Fluphenazine
IUPAC标准名
2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol
IUPAC传统名
2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol
别名
Flufenazine

产品登记号

CAS号 69-23-8

产品性质

生物活性机理 Dopamine-turnover stimulant in the forebrain
生物活性机理 Postsynaptic dopamine-antagonist in: basal ganglia; hypothalamus; limbic-system; brain-stem; medulla
生物活性机理 Mechanism of action not fully understood.
生物活性机理 Calmodulin-antagonist
生物活性机理 Dopamine-antagonist
生物活性机理 Dopamine-release inhibitor
生物活性机理 Increases neuronal firing-rate in the midbrain
应用领域 Tranquilliser
应用领域 Neuroleptic
应用领域 Psychosedative

产品详细信息

参考文献

  • Yale, H.L. et al., J.A.C.S., 1960, 82, 2039, (synth)
  • U.K. Pat., 1960, 829 246; CA, 54, 17428
  • U.K. Pat., 1960, 833 473; CA, 54, 21143
  • Ger. Pat., 1964, 1 165 602; CA, 60, 15886, (deriv)
  • U.S. Pat., 1965, 3 194 733; CA, 64, 5114, (derivs)
  • Gowda, H.S. et al., Rev. Roum. Chim., 1977, 22, 745; CA, 87, 126635a, (use)
  • Curry, S.H. et al., Br. J. Clin. Pharmacol., 1979, 7, 325, (metab)
  • Kreyenbuehl, B. et al., Pharm. Acta Helv., 1979, 54, 197, (uv, ir)
  • Clarke, G., Anal. Profiles Drug Subst., 1980, 9, 275, (rev, decanoate)
  • Shetty, H.U. et al., Biomed. Mass Spectrom., 1983, 10, 601, (ms)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6546; 7787; 7963, (synonyms)
  • Phenothiazines and 1,4-Benzothiazines, (ed. Gupta, R.R.), Elsevier, Amsterdam, 1988, (book, pharmacol)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 596
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, FMP000; PMI250; TJW500