Sparfloxacin

• 产品号: Bio-0774
• CAS号: 110871-86-8
• 分子式: C19H22F2N4O3
• 分子量: 392.3997864

产品别名

• 标题: Sparfloxacin
• IUPAC标准名: 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• IUPAC传统名: 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• 别名: Spara; Zagam

产品登记号

• CAS号: 110871-86-8

产品性质

• 应用领域: Broad spectrum antibacterial agent
• 应用领域: Leprostatic and antitubercular agent
• 生物活性机理: Inhibitor of bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription.
• 生物活性机理: Quinolones can enter cells easily and therefore are often used to treat intracellular pathogens such as Legionella pneumophila and Mycoplasma pneumoniae.
• 生物活性机理: For many gram-negative bacteria DNA gyrase is the target, whereas topoisomerase IV is the target for many gram-positive bacteria.
• 生物活性机理: Eukaryotic cells do not contain DNA gyrase or topoisomerase IV.

参考文献

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