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Sulfafurazole

产品号 Bio-0765 公司名称 InterBioScreen
CAS号 127-69-5 公司网站 http://www.ibscreen.com
分子式 C11H13N3O3S 电 话 +7 49652 40091
分子量 267.30422 传 真 +7 49652 40092
纯 度 电子邮件 screen@ibscreen.chg.ru
保 存 Chembase数据库ID: 148

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产品别名

标题
Sulfafurazole
IUPAC标准名
4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
IUPAC传统名
4-amino-N-(dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide
别名
Neoxazol
Soxomide
Sulfisoxazole
Thiasin
Amidoxal
Gantrisin

产品登记号

CAS号 127-69-5

产品性质

应用领域 Antiseptic
应用领域 Protozoacide
应用领域 Short-acting sulfonamide used for urinary tract infections.
应用领域 Low acute toxicity
生物活性机理 Folate antagonist
生物活性机理 Restrict folate synthesis through competitive antagonism of PABA

产品详细信息

参考文献

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  • Hoeprich, P.D., Antimicrob. Agents Chemother., 1967, 697, (pharmacol)
  • Rudy, B.C. et al., Anal. Profiles Drug Subst., 1973, 2, 487, (rev, synth)
  • Manzo, R.H. et al., J. Pharm. Sci., 1973, 62, 152, (uv)
  • IARC Monog., 1980, 24, 275; Suppl. 7, 347; Suppl. 6, 502, (rev, tox)
  • Chatterjee, C. et al., Acta Cryst. B, 1982, 38, 1845, (cryst struct)
  • Bult, A., Pharm. Weekbl., Sci. Ed., 1983, 5, 77, (cmr, tautom)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1971
  • Kirk-Othmer Encycl. Chem. Technol., 4th edn., Wiley, 1991, 2, 876, (rev)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 207
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, SNN500