Pentoxifylline

• 产品号: Bio-0744
• CAS号: 6493-05-6
• 分子式: C13H18N4O3
• 分子量: 278.30702

产品别名

• 标题: Pentoxifylline
• IUPAC标准名: 3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• IUPAC传统名: 3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
• 别名: Azupentat; Pentoflux; Agapurin; Vazofirin; Torental

产品登记号

• CAS号: 6493-05-6

产品性质

• 应用领域: It is used to treat intermittent claudication resulting from obstructed arteries in the limbs, and vascular dementia
• 应用领域: Pentoxifylline improves blood flow through blood vessels and therefore helps with blood circulation in the arms and legs (e.g. intermittent claudication)
• 应用领域: It also helps prevent strokes, can be used in managing sickle cell disease and improves blood flow to the brain
• 应用领域: Pentoxifylline has also been used to treat nausea and headaches in the mountains (altitude sickness).
• 生物活性机理: Inhibits erythrocyte phosphodiesterase, resulting in an increase in erythrocyte cAMP activity. Subsequently, the erythrocyte membrane becomes more resistant to deformity
• 生物活性机理: Along with erythrocyte activity, pentoxifylline also decreases blood viscosity by reducing plasma fibrinogen concentrations and increasing fibrinolytic activity

参考文献

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