Nifedipine

• 产品号: Bio-0733
• CAS号: 21829-25-4
• 分子式: C17H18N2O6
• 分子量: 346.33462

产品别名

• 标题: Nifedipine
• IUPAC标准名: 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC传统名: 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 别名: Nimodrel; Adalat; Nifensar XL; Glopir; Procardia; Nifedicor; Adipine; Cardilate; Coracten; Fenihidine; Hypolar Retard; Nifecor; Nifedipress; Nifelat; Nifedotard; Nivaten; Tensipine; Angiopine; Calanif; Calcilat; Coroday; Fortipine; Slofedipine

产品登记号

• CAS号: 21829-25-4

产品性质

• 应用领域: Coronary vasodilator
• 应用领域: Antihypertensive agent
• 应用领域: Used to treat Prinzmetal's angina, hypertension, and other vascular disorders such as Raynaud's phenomenon
• 生物活性机理: Calcium channel blocker
• 生物活性机理: Inhibits the influx of extracellular calcium through myocardial and vascular membrane pores by physically plugging the channel
• 生物活性机理: The decrease in intracellular calcium inhibits the contractile processes of smooth muscle cells,
• 生物活性机理: causing dilation of the coronary and systemic arteries,
• 生物活性机理: increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

参考文献

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