Alpha-Acetyldigoxin

• 产品号: Bio-0688
• CAS号: 5511-98-8
• 分子式: C43H66O15
• 分子量: 822.97514

产品别名

• 标题: Alpha-Acetyldigoxin
• IUPAC标准名: (2R,3R,4S,6S)-6-{[(2R,3S,4S,6S)-6-{[(2R,3S,4S,6R)-6-{[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-11,16-dihydroxy-2,15-dimethyl-14-(5-oxo-2,5-dihydrofuran-3-yl)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-5-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-3-hydroxy-2-methyloxan-4-yl acetate
• IUPAC传统名: (2R,3R,4S,6S)-6-{[(2R,3S,4S,6S)-6-{[(2R,3S,4S,6R)-6-{[(1S,2S,5S,7R,10R,11S,14R,15S,16R)-11,16-dihydroxy-2,15-dimethyl-14-(5-oxo-2,5-dihydrofuran-3-yl)tetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadecan-5-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2-methyloxan-3-yl]oxy}-3-hydroxy-2-methyloxan-4-yl acetate
• 别名: Lanatilin; Digoride B; Dioxanin; Decardil; Sandolanid

产品登记号

• CAS号: 5511-98-8

产品性质

• 应用领域: Cardiant
• 应用领域: Cardioglycoside
• 生物活性机理: Inotropic-POS
• 生物活性机理: NA-K-Atpase inhibitor
• 生物活性机理: Increases intracellular calcium ion concentration.

参考文献

• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 1063C; 1064B, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 606B; 608A, (nmr)
• Vine, J. et al., Biomed. Mass Spectrom., 1979, 6, 415, (ms)
• Foss, P.R.B. et al., Anal. Profiles Drug Subst., 1980, 9, 207, (rev, synth, anal, props)
• Aronson, J.K. et al., Clin. Pharmacokinet., 1980, 5, 136, (rev)
• Brown, L. et al., J.C.S. Perkin 1, 1981, 1779, (cmr)
• Marks, V. et al., Ther. Drug Monit., 1981, 415, (rev, anal)
• Jin, H. et al., Can. J. Chem., 1983, 61, 2442-2444, (synth)
• Wisener, K. et al., Helv. Chim. Acta, 1985, 68, 300, (synth)
• Soldin, S.J., Clin. Chem. (Winston-Salem, N.C.), 1986, 32, 5, (rev, pharmacol)
• Woods, K.L., J. Clin. Hosp. Pharm., 1986, 11, 11, (rev, pharmacol, tox)
• Textbook of Adverse Drug Reactions, 4th edn., (ed. Davies, D.M.), Oxford University Press, 1991, 106; 621
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 665; 666
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 11681; 11746; 11747, (synonyms)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, ACH500; ACI000; ACI250; MJD300; DKN400; ACH750; DKL800