Testosterone

• 产品号: Bio-0678
• CAS号: 58-22-0
• 分子式: C19H28O2
• 分子量: 288.42442

产品别名

• 标题: Testosterone
• IUPAC标准名: (1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC传统名: (1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• 别名: Andropatch; Atmos

产品登记号

• CAS号: 58-22-0

产品性质

• 应用领域: Used in the treatment of male hypogonadism (transdermal administration)
• 生物来源: Constit. of human urine
• 生物活性机理: Androgen
• 生物活性机理: FSH antagonist.
• 生物活性机理: ICSH antagonist
• 生物活性机理: The steroid receptor complex is transported to the nucleus where it initiates transcription events and cellular changes related to androgen action
• 生物活性机理: High dose: spermatogenesis inhibitor
• 生物活性机理: Exogenous administration inhibits endogenous release via feedback inhibition of pituitary ICSH
• 生物活性机理: Activity in many tissues appears to depend on reduction to dihydrotestosterone which binds to cytosolic receptor proteins
• 生物活性机理: Gonadotropin antagonist

参考文献

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