Simvastatin

• 产品号: Bio-0672
• CAS号: 79902-63-9
• 分子式: C25H38O5
• 分子量: 418.56622

产品别名

• 标题: Simvastatin
• IUPAC标准名: (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
• IUPAC传统名: (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
• 别名: Zocord; Lipex; Synvinolin; Lodales; Denan; Zocor; Sinvacor; Colemin; Liponorm; Medipo; Pantok; Sivastin; Velastatin

产品登记号

• CAS号: 79902-63-9

产品性质

• 应用领域: Antiarteriosclerotic
• 应用领域: Used in the treatment of hypercholesterolaemia, and to reduce risk of death in patients with coronary heart disease and high serum cholesterol levels
• 生物来源: Metab. of Aspergillus terreus and Monascus spp.*
• 生物活性机理: HMG-CoA reductase inhibitor
• 生物活性机理: Increases HDL cholesterol levels
• 生物活性机理: Decreases LDL cholesterol levels, VLDL cholesterol levels and plasma triglycerides
• 生物活性机理: Cholesterol synthesis inhibitor

参考文献

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