Isoflupredone

• 产品号: Bio-0670
• CAS号: 338-95-4
• 分子式: C21H27FO5
• 分子量: 378.4344832

产品别名

• 标题: Isoflupredone
• IUPAC标准名: (1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• IUPAC传统名: (1R,2S,10S,11S,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• 别名: 9-Fluoroprednisolone; Deltafludrocortisone

产品登记号

• CAS号: 338-95-4

产品性质

• 应用领域: Antiinflammatory agent
• 应用领域: Immunosuppressive
• 生物活性机理: Adrenocorticosteroid
• 生物活性机理: ACTH antagonist
• 生物活性机理: ACTH secretion inhibitor
• 生物活性机理: Gluconeogenesis promoter
• 生物活性机理: Glycogen deposition inhibitor
• 生物活性机理: Calcium mobilizer
• 生物活性机理: Phosphorus mobilizer

参考文献

• McAleer, W.J. et al., J.O.C., 1958, 23, 508, (synth)
• Smith, L.L. et al., J.O.C., 1958, 23, 960, (spectra)
• Pechet, M.M. et al., J. Colloid Sci., 1959, 38, 681, (pharmacol)
• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth, ir, pmr, uv)
• Gladiali, S. et al., Chem. Ind. (London), 1977, 982, (synth)
• Martindale, The Extra Pharmacopoeia, 28th/29th edn., Pharmaceutical Press, 1982, 12869