Prednisolone

• 产品号: Bio-0666
• CAS号: 50-24-8
• 分子式: C21H28O5
• 分子量: 360.44402

产品别名

• 标题: Prednisolone
• IUPAC标准名: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• IUPAC传统名: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-5-one
• 别名: Hydeltra; Delta-Cortef; 1-Dehydrocortisol

产品登记号

• CAS号: 50-24-8

产品性质

• 生物活性机理: On binding, the corticoreceptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes.
• 生物活性机理: The DNA bound receptor then interacts with basic transcription factors, causing an increase or decrease in expression of specific target genes, including suppression of IL2 (interleukin 2) expression.
• 生物活性机理: Glucocorticoid receptor agonist.
• 应用领域: Adrenergic agent
• 应用领域: Antiinflammatory agent
• 应用领域: Antineoplastic agent

参考文献

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