Prednisone acetate

• 产品号: Bio-0655
• CAS号: 125-10-0
• 分子式: C23H28O6
• 分子量: 400.46482

产品别名

• 标题: Prednisone acetate
• IUPAC标准名: 2-[(1S,2R,10S,11S,14R,15S)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethyl acetate
• IUPAC传统名: 2-[(1S,2R,10S,11S,14R,15S)-14-hydroxy-2,15-dimethyl-5,17-dioxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl]-2-oxoethyl acetate
• 别名: Delcortin; Nisone; Delta-Corlin; Cortancyl

产品登记号

• CAS号: 125-10-0

产品性质

• 应用领域: Immunosuppressive
• 应用领域: Antiinflammatory
• 生物来源: Obt. from pregn-4-ene-3,11,20-trione by incubation with Corynebacterium simplex
• 生物活性机理: ACTH antagonist
• 生物活性机理: Corticosteroid
• 生物活性机理: ACTH secretion inhibitor
• 生物活性机理: Gluconeogenesis promoter
• 生物活性机理: Glycogen deposition inhibitor
• 生物活性机理: Calcium mobilizer
• 生物活性机理: Phosphorus mobilizer

参考文献

• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 587B, (nmr)
• Nobile, A. et al., J.A.C.S., 1955, 77, 4184, (synth)
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• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth)
• Gardi, R. et al., Gazz. Chim. Ital., 1963, 93, 431, (ir, uv)
• Tseikinskii, V.M. et al., Bioorg. Khim., 1979, 5, 1677, (cryst struct)
• Pickup, M.E., Clin. Pharmacokinet., 1979, 4, 111, (rev)
• Hickey, J.P. et al., J. Magn. Reson., 1980, 38, 501, (cmr)
• Gambertoglio, J.G. et al., J. Pharmacokinet. Biopharm., 1980, 8, 1, (rev)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 6213
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 738
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, PLZ000; PLZ100