Prednisone

• 产品号: Bio-0649
• CAS号: 53-03-2
• 分子式: C21H26O5
• 分子量: 358.42814

产品别名

• 标题: Prednisone
• IUPAC标准名: (1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-5,17-dione
• IUPAC传统名: (1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-5,17-dione

产品登记号

• CAS号: 53-03-2

产品性质

• 应用领域: Immunosuppressive
• 应用领域: Antiinflammatory
• 生物活性机理: Corticosteroid
• 生物活性机理: ACTH antagonist
• 生物活性机理: ACTH secretion inhibitor
• 生物活性机理: Phosphorus mobilizer
• 生物活性机理: Glycogen deposition inhibitor
• 生物活性机理: Gluconeogenesis promoter
• 生物活性机理: Calcium mobilizer

参考文献

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• Ger. Pat., 1960, 1 090 208; CA, 55, 26044b, (sulfate)
• Herzog, H.L. et al., Tetrahedron, 1962, 18, 581, (synth)
• Gardi, R. et al., Gazz. Chim. Ital., 1963, 93, 431, (ir, uv)
• Pickup, M.E., Clin. Pharmacokinet., 1979, 4, 111, (rev)
• Hickey, J.P. et al., J. Magn. Reson., 1980, 38, 501, (cmr)
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