Hydrocortisone

• 产品号: Bio-0648
• CAS号: 50-23-7
• 分子式: C21H30O5
• 分子量: 362.4599

产品别名

• 标题: Hydrocortisone
• IUPAC标准名: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• IUPAC传统名: (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-en-5-one
• 别名: Hydrocortal; Cortisol;11beta,17alpha,21-Trihydroxyprogesterone; Reichstein's Substance M;Cortef; Hytone; Kendall's compound F; Cortenema; Efcortelan;Ficortril; Hydrocortone

产品登记号

• CAS号: 50-23-7

产品性质

• 应用领域: Topical antiinflammatory agent
• 应用领域: Antiallergic
• 应用领域: Immunosuppressive
• 生物来源: Adrenal cortical hormone
• 生物活性机理: Glucocorticoid
• 生物活性机理: ACTH secretion inhibitor
• 生物活性机理: Phosphorus mobilizer
• 生物活性机理: Gluconeogenesis promoter
• 生物活性机理: Glycogen deposition inhibitor
• 生物活性机理: Calcium mobilizer

参考文献

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• Shirasaka, M., Chem. Pharm. Bull., 1961, 9, 152, (synth)
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• Fiegel, G., Arzneim.-Forsch., 1975, 25, 560, (use)
• Genard, P., Org. Mass Spectrom., 1979, 12, 396, (pmr)
• Castellano, E.E. et al., Acta Cryst. B, 1980, 36, 3063, (cryst. struct)
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• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, BAV275; HHR000; CNS750; HHQ800; HHQ825; HHQ850; HHQ875