Streptomycin

• 产品号: Bio-0644
• CAS号: 57-92-1
• 分子式: C21H39N7O12
• 分子量: 581.57406

产品别名

• 标题: Streptomycin
• IUPAC标准名: 1-[(1R,2R,3S,4R,5R,6S)-3-carbamimidamido-4-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2,5,6-trihydroxycyclohexyl]guanidine
• IUPAC传统名: 1-[(1R,2R,3S,4R,5R,6S)-3-carbamimidamido-4-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy}-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy}-2,5,6-trihydroxycyclohexyl]guanidine
• 别名: Agrept; Merstep; Agrimycin; Streptomisin; Estreptomicina

产品登记号

• CAS号: 57-92-1

产品性质

• 应用领域: Aminoglycoside antibiotic
• 应用领域: Clinically used broad spectrum antibacterial (tuberculostatic) agent
• 生物来源: Isol. from Streptomyces griseus
• 生物活性机理: Protein synthesis inhibitor
• 生物活性机理: Activity increased in alkaline medium binds irreversibly to the bacterial ribosomal 30S subunit
• 生物活性机理: Blocks the recognition step in protein-synthesis
• 生物活性机理: Causes misreading of the genetic code
• 生物活性机理: Causes ribosomal dissociation from messenger RNA
• 生物活性机理: Apoptosis-inducer

参考文献

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