Khellin

• 产品号: Bio-0626
• CAS号: 82-02-0
• 分子式: C14H12O5
• 分子量: 260.24208

产品别名

• 标题: Khellin
• IUPAC标准名: 4,9-dimethoxy-7-methyl-5H-furo[3,2-g]chromen-5-one
• IUPAC传统名: 4,9-dimethoxy-7-methyl-5H-furo[3,2-g]chromen-5-one
• 别名: Eskel; Visammin; Kellin

产品登记号

• CAS号: 82-02-0

产品性质

• 应用领域: Displays a range of pharmacol. activity including anthelmintic, antianaphylactic, antiarteriosclerotic, antiasthmatic and antidiabetic props.
• 应用领域: Spasmolytic
• 应用领域: Bronchodilator
• 应用领域: Vasodilator
• 应用领域: Shows antitussive, antiulcerogenic, bronchodilator and vasodilator props.
• 应用领域: Exhibits spasmolytic activity, used in treatment of heart disease
• 应用领域: Photochemotherapeutic agent for treatment of vitiligo
• 生物来源: Constit. of the fruit of Ammi visnaga
• 生物活性机理: Cholesterol antagonist

参考文献

• Beale, J.P. et al., Cryst. Struct. Commun., 1973, 2, 125, (cryst struct)
• Carpy, A. et al., Cryst. Struct. Commun., 1979, 8, 835, (cryst struct)
• Elgamal, M.H.A. et al., Phytochemistry, 1979, 18, 139, (cmr)
• Hassan, M.A. et al., Anal. Profiles Drug Subst., 1980, 9, 371, (rev)
• Gammill, R.B. et al., J.O.C., 1983, 48, 3863, (synth)
• Yamashita, A., J.A.C.S., 1985, 107, 5823, (synth, bibl)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 3052, (synonyms)
• Nagasawa, K. et al., Heterocycles, 1988, 27, 1159, (synth)
• Morliere, P. et al., J. Invest. Dermatol., 1988, 90, 720, (photosensitising prop)
• Reed, M.W. et al., J.O.C., 1988, 53, 4166, (synth)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1024
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, AHK750
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 173C, (nmr)
• Aldrich Library of FT-IR Spectra: Vapor Phase, 1989, 3, 1506B, (ir)
• Baxter, R.A. et al., J.C.S., Suppl., 1949, 30, (synth)
• Clarke, J.R. et al., J.C.S., 1949, 302, (synth)
• Gardner, T.S. et al., J.O.C., 1950, 15, 841, (synth)
• Geissman, T.A. et al., J.A.C.S., 1951, 73, 1280, (synth)
• Bencze, W. et al., Helv. Chim. Acta, 1956, 39, 923, (Khellinol)
• Badawi, M.M. et al., Chem. Ind. (London), 1966, 498, (ms)