您当前所在的位置:首页 > 产品中心 > 产品信息
Isbufylline_分子结构_CAS_90162-60-0)
点击图片或这里关闭

Isbufylline

产品号 Bio-0434 公司名称 InterBioScreen
CAS号 90162-60-0 公司网站 http://www.ibscreen.com
分子式 C11H16N4O2 电 话 +7 49652 40091
分子量 236.27034 传 真 +7 49652 40092
纯 度 电子邮件 screen@ibscreen.chg.ru
保 存 Chembase数据库ID: 179803

产品价格信息

请登录

产品别名

标题
Isbufylline
IUPAC标准名
1,3-dimethyl-7-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
IUPAC传统名
1,3-dimethyl-7-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
别名
N -(2-Methylpropyl)
7-Isobutyltheophylline
Theophylline

产品登记号

CAS号 90162-60-0

产品性质

应用领域 Bronchodilator
应用领域 Antiasthmatic
生物活性机理 Adenosine receptor antagonist
生物活性机理 CNS-stimulant
生物活性机理 Purine antagonist
生物活性机理 Phosphodiesterase inhibitor
生物活性机理 Gastric-secretion stimulator
生物活性机理 Causes accumulation of cyclic-AMP

产品详细信息

参考文献

  • Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 214B, (nmr)
  • Blout, E.R. et al., J.A.C.S., 1950, 72, 479, (ir)
  • Spiteller, G. et al., Monatsh. Chem., 1962, 93, 632, (ms)
  • Twanmoh, L.-M. et al., J. Het. Chem., 1973, 10, 187, (pmr)
  • Takayama, S. et al., Chem. Pharm. Bull., 1974, 22, 1200, (synth, uv)
  • Nicolau, C. et al., Z. Naturforsch., C, 1974, 29, 475, (cmr)
  • Cohen, J.L., Anal. Profiles Drug Subst., 1975, 4, 466, (rev, ir, pmr, uv, ms, anal)
  • Goeber, B. et al., Pharmazie, 1978, 33, 717, (ms)
  • Naqvi, A.A. et al., J. Appl. Crystallogr., 1981, 14, 464, (cryst struct)
  • Nishijo, J. et al., Chem. Pharm. Bull., 1982, 30, 391, (salts)
  • Belg. Pat., 1983, 897 492; CA, 100, 209534e, (Isbufylline, synth)
  • Bukowsky, M. et al., Ann. Intern. Med., 1984, 101, 63, (rev, pharmacol)
  • Weinberger, M., J. Allergy Clin. Immunol., 1984, 73, 525, (rev, pharmacol, tox)
  • Grant, J.A. et al., J. Allergy Clin. Immunol., 1986, 78, 669, (rev, pharmacol)
  • Rowe, D.J.F. et al., Ann. Clin. Biochem., 1988, 25, 4, (rev, pharmacol, tox, metab)
  • Agostini, O. et al., Arzneim.-Forsch., 1990, 40, 1089, (Isbufylline, props, pmr, ms, ir, uv, cmr, cryst struct)
  • Manzini, S. et al., Arzneim.-Forsch., 1990, 40, 1205, (Isbufylline, pharmacol)
  • Atta-ur-Rahman et al., The Alkaloids, 1990, 38, 232, (spectra)
  • IARC Monog., 1991, 51, 391, (rev, tox)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 1314; 1315; 1319
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 7th edn., Akademie-Verlag, 1994, 793, (synonyms)
  • Ebisuzaki, Y. et al., Acta Cryst. C, 1997, 53, 777-779, (cryst struct)
  • Markham, A. et al., Drugs, 1998, 56, 1081-1091, (rev)
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, TEP000; TEP500