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Nitrofurantoin

产品号 Bio-0352 公司名称 InterBioScreen
CAS号 67-20-9 公司网站 http://www.ibscreen.com
分子式 C8H6N4O5 电 话 +7 49652 40091
分子量 238.15704 传 真 +7 49652 40092
纯 度 电子邮件 screen@ibscreen.chg.ru
保 存 Chembase数据库ID: 104426

产品价格信息

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产品别名

标题
Nitrofurantoin
IUPAC标准名
1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione
IUPAC传统名
1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione
别名
Macrodantin
Urantoin
Berkfurin
Furadantin

产品登记号

CAS号 67-20-9

产品性质

应用领域 Antibacterial agent used to treat urinary-tract infections and Staphylococcus aureus
应用领域 Staphylococcus saprophyticus
应用领域 bactericidal at high-dose
应用领域 some strains of Klebsiella; some strains of Enterobacter.
应用领域 activity against: Escherichia coli; Enterococcus
应用领域 Antiseptic
生物活性机理 Damaging bacterial DNA, ribosomal proteins, DNA, effecting respiration, pyruvate metabolism and other macromolecules within the cell

产品详细信息

参考文献

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  • Chamberlain, R.E., J. Antimicrob. Chemother., 1976, 2, 325, (pharmacol, rev)
  • Bryan, G.T., Carcinog. - Compr. Surv., (Ed. Bryan, G.T.), Vol 4. Nitrofurans, Raven Press, N.Y., 1978, (book)
  • Gleckman, R. et al., Am. J. Hosp. Pharm., 1979, 36, 342, (rev)
  • Baeva, V. et al., CA, 1983, 98, 125968, (synth)
  • Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 824, (synonyms)
  • IARC Monog., 1990, 50, 211, (rev, tox)
  • Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 187
  • Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, NGE000