Oxitriptan

• 产品号: Bio-0296
• CAS号: 4350-09-8
• 分子式: C11H12N2O3
• 分子量: 220.22458

产品别名

• 标题: Oxitriptan
• IUPAC标准名: (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
• IUPAC传统名: (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
• 别名: Levothym; Serotonyl; Triptene

产品登记号

• CAS号: 4350-09-8

产品性质

• 应用领域: Antidepressant
• 应用领域: Psychostimulant
• 生物来源: Metab. of Chromobacterium violaceum, constit. of the seeds of Griffonia simplicifolia. Occurs in large amts. in Panaeolus sphinctrinus and other Panaeolus spp.
• 生物活性机理: Precusor of 5-hydroxytryptamine

参考文献

• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 146B, (nmr)
• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 673C; 673D, (ir)
• Witkop, B. et al., J.A.C.S., 1954, 76, 5579, (synth)
• Morris, A.J. et al., J.O.C., 1957, 22, 306, (resoln, abs config)
• Biochem. Prep., 1962, 9, 92, (synth)
• Tyler, V.E. et al., J. Pharm. Sci., 1964, 53, 462, (isol)
• Bell, E.A. et al., Nature (London), 1966, 210, 529, (isol)
• Wakahara, A. et al., Bull. Chem. Soc. Jpn., 1973, 46, 2475, (cryst struct)
• Frahn, J.L. et al., Aust. J. Chem., 1974, 27, 1367, (synth, deriv)
• Iriuchijima, S. et al., Agric. Biol. Chem., 1978, 42, 843, (synth, deriv)
• Francis, P. et al., Biomed. Mass Spectrom., 1980, 7, 294, (ms, deriv)
• Van Praag, H.M., Neuropharmacology, 1983, 22, 433, (rev)
• Irie, K. et al., Chem. Pharm. Bull., 1984, 32, 2126, (synth)
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, HOA575; HOA600; HON800; HOO000; HOO100