Inosine

• 产品号: Bio-0209
• CAS号: 58-63-9
• 分子式: C10H12N4O5
• 分子量: 268.22608

产品别名

• 标题: Inosine
• IUPAC标准名: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
• IUPAC传统名: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
• 别名: Trophicardyl; Inosie; Oxiamine; Hypoxanthosine; Hypoxanthine riboside; Carnine

产品登记号

• CAS号: 58-63-9

产品性质

• 应用领域: Cardiotonic
• 应用领域: Used to treat cardiac disorders
• 生物来源: Prod. by microorganisms, e.g. Bacillus subtilis, E. coli, Saccharomyces cerevisiae, Fusarium spp.
• 生物活性机理: Activates cellular functions by base pairs with Adenine HFN72-P, Cytosine HDR44-O or Uracil BTP40-U

参考文献

• Aldrich Library of FT-IR Spectra, 1st edn., 1985, 2, 712B, (ir)
• Aldrich Library of 13C and 1H FT NMR Spectra, 1992, 3, 215C, (nmr)
• Gulland, J.M. et al., J.C.S., 1936, 765, (struct)
• Hall, R.H., Biochem. Biophys. Res. Commun., 1963, 13, 394, (isol, deriv)
• Kinichi, I. et al., Chem. Pharm. Bull., 1966, 14, 1377, (synth)
• Japan. Pat., 1968, 68 13 215; CA, 70, 47808, (synth, isopropylidene)
• Munns, A.R.I. et al., Acta Cryst. B, 1970, 26, 1114, (cryst struct)
• Ger. Pat., 1972, 2038262; CA, 76, 99993e, (synth)
• Chenon, M.T. et al., J.A.C.S., 1975, 97, 4627, (cmr)
• Westhof, E. et al., Z. Naturforsch., C, 1975, 30, 131, (pmr)
• Hawkes, G.E. et al., J.C.S. Perkin 2, 1977, 1268, (N-15 nmr)
• Yamazaki, A. et al., J. Het. Chem., 1978, 15, 353, (rev, synth)
• Aviado, D.M., J. Pharmacol., 1983, 14, 47, (rev, pharmacol)
• Campoli-Richards, D.M. et al., Drugs, 1986, 32, 383, (rev, Inosine pranobex)
• Negwer, M., Organic-Chemical Drugs and their Synonyms, 6th edn., Akademie-Verlag, 1987, 1551
• De Simone, C. et al., Int. J. Immunopharmacol., 1991, 13, 19, (rev, Inosine pranobex)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 548; 1379
• Lewis, R.J., Sax's Dangerous Properties of Industrial Materials, 8th edn., Van Nostrand Reinhold, 1992, IDE000