Olanzapine

• 产品号: Bio-0169
• CAS号: 132539-06-1
• 分子式: C17H20N4S
• 分子量: 312.4325

产品别名

• 标题: Olanzapine
• IUPAC标准名: 5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.0^3,^7]tetradeca-1(14),3(7),5,8,10,12-hexaene
• IUPAC传统名: 5-methyl-8-(4-methylpiperazin-1-yl)-4-thia-2,9-diazatricyclo[8.4.0.0^3,^7]tetradeca-1(14),3(7),5,8,10,12-hexaene
• 别名: Zalasta; Zolafren; Zyprexa; Zyprexa Zydis; Olzapin

产品登记号

• CAS号: 132539-06-1

产品性质

• 应用领域: Antipsychotic agent
• 应用领域: Used in the treatment of schizophrenia and bipolar disorder
• 生物活性机理: 5HT(2) and dopamine D2 receptor antagonist

参考文献

• Eur. Pat., 1991, Lilly, 454 436; CA, 116, 83703u, (synth, pharmacol)
• Moore, N.A. et al., J. Pharmacol. Exp. Ther., 1992, 262, 545, (pharmacol)
• Fulle, R.W. et al., Res. Commun. Chem. Pathol. Pharmacol., 1992, 77, 87, (pharmacol)
• Fulton, B. et al., Drugs, 1997, 53, 281-298, (rev)
• Martindale, The Extra Pharmacopoeia, 32nd edn., Pharmaceutical Press, 1999, 683
• Bhana, N. et al., Drugs, 2001, 61, 111-161, (rev)