Loteprednol Etabonate

• 产品号: Bio-0130
• CAS号: 82034-46-6
• 分子式: C24H31ClO7
• 分子量: 466.95174

产品别名

• 标题: Loteprednol Etabonate
• IUPAC标准名: chloromethyl (2R,14R,15S,17S)-14-[(ethoxycarbonyl)oxy]-17-hydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-14-carboxylate
• IUPAC传统名: chloromethyl (2R,14R,15S,17S)-14-[(ethoxycarbonyl)oxy]-17-hydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-diene-14-carboxylate
• 别名: Alrex; Loteflam; Zylet; Lotemax

产品登记号

• CAS号: 82034-46-6

产品性质

• 应用领域: Antiinflammatory agent
• 应用领域: Used in ophthalmology
• 生物活性机理: Corticosteroid

参考文献

• Belg. Pat., 1981, Otsuka Pharm, 889 563; CA, 97, 6651n, (synth, pharmacol)
• Druzgala, P. et al., J. Steroid Biochem., 1991, 38, 149, (synth, pmr, ir)
• Bodor, N.S. et al., Steroids, 1991, 56, 434, (pharmacol)
• Bodor, N. et al., Pharm. Res., 1992, 9, 1275, (metab)
• Howes, J.F. et al., J. Ocul. Pharmacol., 1994, 10, 289, (activity)
• Graul, A., Drugs of the Future, 1997, 22, 1086