Dorzolamide Hydrochloride

• 产品号: Bio-0123
• CAS号: 130693-82-2
• 分子式: C10H17ClN2O4S3
• 分子量: 360.90098

产品别名

• 标题: Dorzolamide Hydrochloride
• IUPAC标准名: (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1λ^6,7-thieno[2,3-b][1λ^6]thiopyran-6-sulfonamide hydrochloride
• IUPAC传统名: (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1λ^6,7-thieno[2,3-b][1λ^6]thiopyran-6-sulfonamide hydrochloride

产品登记号

• CAS号: 130693-82-2

产品性质

• 应用领域: Antiglaucoma agent
• 成盐信息: HCl
• 生物活性机理: Carbonic anhydrase inhibitor

参考文献

• Eur. Pat., 1988, Merck, 296 879; CA, 110, 192805a, (synth, pharmacol)
• Wang, R.F. et al., Arch. Ophthalmol. (Chicago), 1990, 108, 511; 1991, 109, 1297, (pharmacol)
• Blacklock, T.J. et al., J.O.C., 1993, 58, 1672, (synth, pmr, cmr, ir, uv)
• Matuszewski, B.K. et al., Pharm. Res., 1994, 11, 449, (resoln)
• Quint, M.-P., Anal. Profiles Drug Subst., 1999, 26, 283-318, (rev)