Perindopril tert-Butylamine salt

• 产品号: Bio-0079
• CAS号: 107133-36-8
• 分子式: C21H39N3O5
• 分子量: 413.55146

产品别名

• 标题: Perindopril tert-Butylamine salt
• IUPAC标准名: 2-methylpropan-2-aminium (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-carboxybutyl]amino}propanoyl]-octahydro-1H-indole-2-carboxylate
• IUPAC传统名: 2-methylpropan-2-aminium (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-carboxybutyl]amino}propanoyl]-octahydro-1H-indole-2-carboxylate
• 别名: Coversil; Electan; Procaptan

产品登记号

• CAS号: 107133-36-8

产品性质

• 应用领域: Antihypertensive agent
• 成盐信息: tert-Butylamine
• 生物活性机理: ACE inhibitor

参考文献

• ACE Inhibitors: Current Use and Future Prospects, (Ed. Schachter, M.), Martin Dunitz, 1995, (book)
• McClellan, K.J. et al., Drugs, 1999, 58, 297-302
• Hurst, M. et al., Drugs, 2001, 61, 867-896, (rev)
• Matheson, A.J. et al., Drugs, 2001, 61, 1211-1229, (rev)
• Vincent, M. et al., Tet. Lett., 1982, 23, 1677, (synth)
• Laubie, M. et al., J. Cardiovasc. Pharmacol., 1984, 6, 1076, (pharmacol)
• Unger, T. et al., J. Cardiovasc. Pharmacol., 1986, 8, 276; 346, (pharmacol)
• Reid, J.L. et al., Clin. Exp. Hypertens., Part A, 1987, 9, 361, (rev)
• Macfadyen, R.J. et al., Drugs, Suppl. 1, 1990, 39, 49, (rev, Perindopril)
• Todd, P.A. et al., Drugs, 1991, 42, 90, (rev)
• Scalbert, E. et al., J. Cardiovasc. Pharmacol., 1991, 18, S25, (rev, perindopril)
• Pascard, C. et al., J. Med. Chem., 1991, 34, 663, (synth, cryst struct, sar)
• Reid, J.L. et al., S. Afr. Med. J., Suppl., 1991, 1, (rev)
• Am. J. Med., Suppl. 4B, 1992, 92, 39S; 69S; 79S; 84S; 91S; 95S; 98S; 102S, (rev)
• Atkinson, J., Cardiovasc. Drug Rev., 1992, 10, 446, (rev, perindopril)
• Vincent, M. et al., Drug Des. Discovery, 1992, 9, 11, (synth, isomers, activity)
• Bouchet, J.P. et al., Magn. Reson. Chem., 1992, 30, 1186, (pmr, cmr, conformn)
• Bnner, G. et al., Arzneim.-Forsch., 1993, 43, 852, (clin trials)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 382
• Lerebours, G. et al., Can. J. Cardiol., 1994, 10, 3D, (rev)