Mometasone Furoate

• 产品号: Bio-0063
• CAS号: 83919-23-7
• 分子式: C27H30Cl2O6
• 分子量: 521.4295

产品别名

• 标题: Mometasone Furoate
• IUPAC标准名: (1R,2S,13R,14R,15S,17S)-1-chloro-14-(2-chloroacetyl)-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl furan-2-carboxylate
• IUPAC传统名: (1R,2S,13R,14R,15S,17S)-1-chloro-14-(2-chloroacetyl)-17-hydroxy-2,13,15-trimethyl-5-oxotetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-3,6-dien-14-yl furan-2-carboxylate
• 别名: Elocon; Elocom

产品登记号

• CAS号: 83919-23-7

产品性质

• 应用领域: Antiinflammatory
• 应用领域: Antiallergic agent
• 生物活性机理: Glucocorticoid steroid

参考文献

• Shapiro, E.L. et al., J. Med. Chem., 1987, 30, 1581, (synth, pharmacol, deriv)
• Popper, T.L. et al., J. Steroid Biochem., 1987, 27, 837, (pharmacol)
• Martindale, The Extra Pharmacopoeia, 30th edn., Pharmaceutical Press, 1993, 737
• Prakash, A. et al., Drugs, 1998, 55, 145-163, (pharmacol, rev)
• Onrust, S.V. et al., Drugs, 1998, 56, 725-745, (mometasone furoate, rev)
• Draper, R.W. et al., Tetrahedron, 1999, 55, 3355-3364, (furoate, synth)
• Sharpe, M. et al., Drugs, 2001, 61, 1325-1350, (rev)