Felodipine

• 产品号: Bio-0040
• CAS号: 72509-76-3
• 分子式: C18H19Cl2NO4
• 分子量: 384.25376

产品别名

• 标题: Felodipine
• IUPAC标准名: 3-ethyl 5-methyl (4S)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• IUPAC传统名: 3-ethyl 5-methyl (4S)-4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• 别名: Plendil; Modip; Agon; Feloc; Hydac; Fensel; Plandil; Splendil

产品登记号

• CAS号: 72509-76-3

产品性质

• 应用领域: Antihypertensive agent
• 应用领域: Vasodilator
• 应用领域: Used to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina
• 生物活性机理: Calcium channel blocker
• 生物活性机理: Reversibly competes with nitrendipine and other calcium channel blockers for dihydropyridine binding sites
• 生物活性机理: Blocks voltage-dependent calcium currents in vascular smooth muscle and cultured rabbit atrial cells, and blocks potassium-induced contracture of the rat portal vein
• 生物活性机理: By blocking the calcium channels, inhibits the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes and
• 生物活性机理: results in a decrease of peripheral vascular resistance.

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