Diacerein

• 产品号: Bio-0025
• CAS号: 13739-02-1
• 分子式: C19H12O8
• 分子量: 368.29378

产品别名

• 标题: Diacerein
• IUPAC标准名: 4,5-bis(acetyloxy)-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
• IUPAC传统名: 4,5-bis(acetyloxy)-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
• 别名: Fisiodar; Artrodar

产品登记号

• CAS号: 13739-02-1

产品性质

• 应用领域: Nonsteroidal antiinflammatory agent
• 生物活性机理: Interleukin-1 inhibitor

参考文献

• Hauptmann, H. et al., J.A.C.S., 1950, 72, 1492, (occur)
• Nawa, H. et al., J.O.C., 1961, 26, 979, (struct)
• Romanova, A.S. et al., Khim. Prir. Soedin., 1966, 2, 143; Chem. Nat. Compd. (Engl. Transl.), 1966, 2, 113, (isol, glucosides)
• Murty, V.K. et al., Tetrahedron, 1967, 23, 515, (synth, deriv)
• Romonova, A.S. et al., CA, 1969, 70, 9366, (isol)
• Karrer, W. et al., Konstitution und Vorkommen der Organischen Pflanzenstoffe, 2nd edn., Birkhuser Verlag, Basel, 1972, no. 1297, (occur)
• Ger. Pat., 1977, 2 711 493; CA, 88, 37504k, (synth)
• Hauser, F.M. et al., J.O.C., 1982, 47, 383, (synth)
• Gallagher, P.T. et al., Tet. Lett., 1994, 35, 289, (synth)
• Martindale, The Extra Pharmacopoeia, 31st edn., Pharmaceutical Press, 1996, 34
• Dahms, M. et al., Drug Metab. Dispos., 1997, 25, 442, (metab, bibl)
• Spencer, C.M. et al., Drugs, 1997, 53, 98-106, (Diacerein, rev)