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Streptolydigin

产品号 DB04785 公司名称 DrugBank
CAS号 7229-50-7 公司网站 http://www.ualberta.ca/
分子式 C32H44N2O9 电 话 (780) 492-3111
分子量 600.69976 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 4331

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产品别名

标题
Streptolydigin
IUPAC标准名
(2S)-2-[(2S)-4-[(2E,4E,6R)-6-[(1S,2S,5S,6S,7S)-1,6-dimethyl-8,9-dioxaspiro[bicyclo[3.3.1]nonane-2,2'-oxiran]-3-en-7-yl]-4-methylhepta-2,4-dienoyl]-5-hydroxy-1-[(2S,5S,6S)-5-hydroxy-6-methyloxan-2-yl]-3-oxo-2,3-dihydro-1H-pyrrol-2-yl]-N-methylpropanamide
IUPAC传统名
streptolydigin
别名
Antibiotic D-45
Portamycin

产品登记号

PubChem SID 46505558
PubChem CID 6436180
CAS号 7229-50-7

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产品详细信息

详细说明 (English)
Item Information
Drug Groups experimental
Pharmacology Streptolydigin is an antibiotic which works by blocking nucleic acid chain elongation by binding to the polymerase, thus stopping RNA polymerase activity inside a cell. Specifically, it inhibits the assembly of the RNA polymerase II transcription complex and DNA polymerase III transcription. It is active against a number of gram positive bacteria.
Affected Organisms
Enteric bacteria and other eubacteria
External Links
Wikipedia

参考文献