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Aniracetam

产品号 DB04599 公司名称 DrugBank
CAS号 72432-10-1 公司网站 http://www.ualberta.ca/
分子式 C12H13NO3 电 话 (780) 492-3111
分子量 219.23652 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 4164

产品价格信息

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产品别名

标题
Aniracetam
IUPAC标准名
1-(4-methoxybenzoyl)pyrrolidin-2-one
IUPAC传统名
1-(4-methoxybenzoyl)pyrrolidin-2-one
商标名
Sarpul
Draganon
AMPAMET
别名
1-P-ANISOYL-2-PYRROLIDINONE

产品登记号

CAS号 72432-10-1
PubChem CID 2196
PubChem SID 46506607

产品性质

产品详细信息

详细说明 (English)
Item Information
Drug Groups experimental
Description Compound with anti-depressive properties used as a mental performance enhancer.
Pharmacology Aniracetam possesses a wide range of anxiolytic properties, which may be mediated by an interaction between cholinergic, dopaminergic and serotonergic systems.
Affected Organisms
Humans and other mammals
Half Life 1-2.5 hours
References
Nakamura K, Kurasawa M: Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420(1):33-43. [Pubmed]
Lawrence JJ, Brenowitz S, Trussell LO: The mechanism of action of aniracetam at synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors: indirect and direct effects on desensitization. Mol Pharmacol. 2003 Aug;64(2):269-78. [Pubmed]
External Links
Wikipedia

参考文献

  • Nakamura K, Kurasawa M: Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism. Eur J Pharmacol. 2001 May 18;420(1):33-43. Pubmed
  • Lawrence JJ, Brenowitz S, Trussell LO: The mechanism of action of aniracetam at synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors: indirect and direct effects on desensitization. Mol Pharmacol. 2003 Aug;64(2):269-78. Pubmed