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Gadoversetamide

产品号 DB00538 公司名称 DrugBank
CAS号 131069-91-5 公司网站 http://www.ualberta.ca/
分子式 C20H34GdN5O10 电 话 (780) 492-3111
分子量 661.76146 传 真
纯 度 电子邮件 david.wishart@ualberta.ca
保 存 Chembase数据库ID: 420

产品价格信息

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产品别名

标题
Gadoversetamide
IUPAC标准名
gadolinium(3+) ion 2-[bis({2-[(carboxylatomethyl)({[(2-methoxyethyl)carbamoyl]methyl})amino]ethyl})amino]acetate
IUPAC传统名
gadolinium(3+) 2-[bis({2-[(carboxylatomethyl)({[(2-methoxyethyl)carbamoyl]methyl})amino]ethyl})amino]acetate
商标名
OptiMARK
别名
Gadoversetamide [USAN:INN:BAN]
gadoversetamide

产品登记号

CAS号 131069-91-5
PubChem SID 46504481
PubChem CID 444013

产品性质

产品详细信息

详细说明 (English)
Item Information
Drug Groups approved; investigational
Description Gadoversetamide is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver. It is marketed under the trade name OptiMARK.
Indication Gadoversetamide is an MRI contrast agent used for MRI diagnostic procedures to provide increased enhancement and visualization of lesions of the brain, spine and liver, including tumors.
Affected Organisms
Humans and other mammals
Biotransformation None detected
Half Life Distribution 13.3 ± 6.8 (mean) minutes, elimination 103.6 ± 19.5 (mean) minutes.
Elimination The mean cumulative urinary excretion of gadoversetamide at 72 hours was approximately 93.5% for renal impaired patients and 95.8% for subjects with normal renal function
Distribution * 162 ± 25 mL/kg [normal subjects]
Clearance * 72 +/- 16.3 mL/hr/kg [healthy]
External Links
Wikipedia

参考文献