rac Zosuquidar-d5 Trihydrochloride

• 产品号: Z700872
• 分子式: C32H31F2N3O2
• 分子量: 527.6042464

产品别名

• 标题: rac Zosuquidar-d5 Trihydrochloride
• IUPAC标准名: 1-{4-[(2R,4S,11R)-3,3-difluorotetracyclo[10.4.0.0^2,^4.0^5,^1^0]hexadeca-1(12),5(10),6,8,13,15-hexaen-11-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)(^2H₅)propan-2-ol
• IUPAC传统名: 1-{4-[(2R,4S,11R)-3,3-difluorotetracyclo[10.4.0.0^2,^4.0^5,^1^0]hexadeca-1(12),5(10),6,8,13,15-hexaen-11-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)(^2H₅)propan-2-ol
• 别名: Zosuquidar-d5 Hydrochloride; RS 33295-198-d5; LY 335979-d5; rac-4-[(1aα,6α,10bα)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-1-piperazineethanol-d5 Hydrochloride

产品详细信息

详细说明 (English)

Labelled Zosuquidar (Z700870). Multi-drug resistance (MDR) modulator; selective inhibitor of P-glycoprotein (P-gp). Antineoplastic adjunct (chemosensitizer).

参考文献

• Green, L.J., et al.: Biochem. Pharmacol., 61, 1393 (2001)
• Shepard, R.L., et al.: Int. J. Cancer, 103, 121 (2001)