Zotarolimus-d3

• 产品号: Z700802
• 分子式: C52H79N5O12
• 分子量: 966.20996

产品别名

• 标题: Zotarolimus-d3
• IUPAC标准名: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30R,32S,35R)-1,18-dihydroxy-30-(^2H₃)methoxy-19-methoxy-12-[(2R)-1-[(1S,3R,4R)-3-methoxy-4-(1H-1,2,3,4-tetrazol-1-yl)cyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0^4,^9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
• IUPAC传统名: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30R,32S,35R)-1,18-dihydroxy-30-(^2H₃)methoxy-19-methoxy-12-[(2R)-1-[(1S,3R,4R)-3-methoxy-4-(1,2,3,4-tetrazol-1-yl)cyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0^4,^9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
• 别名: A 179578-d3; 42-(1-Tetrazolyl)rapamycin-d3; (42S)-42-Deoxy-42-(1H-tetrazol-1-yl)rapamycin-d3; ABT 578-d3

产品详细信息

详细说明 (English)

Labelled Zotarolimus. A tetrazole-containing Rapamycin analog as immunomodulator and useful in the treatment of restenosis and immune and autoimmune diseases.

参考文献

• Moses, J., et al.: N. Engl. J. Med., 349, 1315 (2003)
• Ako, J., et al.: J. Am. Coll. Cardiol., 46, 1002 (2003)
• Wagner, et al.: Bioorg. Med. Chem. Lett., 15, 5340 (2003)
• Hong, M., et al.: Circulation, 113, 414 (2003)