Zebularine

• 产品号: Z276000
• CAS号: 3690-10-6
• 分子式: C9H12N2O5
• 分子量: 228.20198
• 保 存: Refrigerator, Under Inert Atmosphere

产品别名

• 标题: Zebularine
• IUPAC标准名: 1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
• IUPAC传统名: 1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 别名: 1-β-D-Ribofuranosyl-2(1H)-pyrimidinone; NSC 309132; Pyrimidin-2-one β-D-Ribofuranoside; 4-Deoxyuridine

产品登记号

• CAS号: 3690-10-6

产品性质

• 外观: White to Off-White Solid
• 熔点: 160-162°C
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: Refrigerator, Under Inert Atmosphere

产品详细信息

详细说明 (English)

It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.

参考文献

• Driscoll, J., et al.: J. Med. Chem., 34, 3280 (1991)
• Ueki, T., et al.: Cancer Res., 60, 1835 (1991)
• Sherr, C., et al.: Cell, 116, 235 (1991)
• Dote, H., et al.: Clin. Cancer Res.,11, 4571 ( 2005),