Zaprinast

• 产品号: Z150000
• CAS号: 37762-06-4
• 分子式: C13H13N5O2
• 分子量: 271.27462
• 保 存: -20°C Freezer

产品别名

• 标题: Zaprinast
• IUPAC标准名: 5-(2-propoxyphenyl)-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
• IUPAC传统名: 5-(2-propoxyphenyl)-3H,6H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one
• 别名: 3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; M&B 22,948; 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one; 8-Aza-2-(2-propoxyphenyl)-6-purinone

产品登记号

• CAS号: 37762-06-4

产品性质

• 外观: Pale Pink Solid
• 熔点: 237-238°C dec.
• 溶解度: DMSO
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of

参考文献

• Burns, F., et al.: Biochem. J., 238, 487 (1992)
• Lugnier, C., et al.: Am. J. Physiol., 262, H654 (1992)