Withaferin A

• 产品号: W499200
• CAS号: 5119-48-2
• 分子式: C28H38O6
• 分子量: 470.59772
• 保 存: -20°C Freezer

产品别名

• 标题: Withaferin A
• IUPAC标准名: (1S,2R,6S,7R,9R,11S,12S,15R,16S)-6-hydroxy-15-[(1S)-1-[(2R)-5-(hydroxymethyl)-4-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl]-2,16-dimethyl-8-oxapentacyclo[9.7.0.0^2,^7.0^7,^9.0^1^2,^1^6]octadec-4-en-3-one
• IUPAC传统名: withaferin A
• 别名: Withaferine; Withaferine A; NSC 273757; (4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic Acid δ-Lactone; (20S,22R)-5,6β-Epoxy-4β,22,27-trihydroxy-1-oxo-5β-ergosta-2,24-dien-26-oic Acid δ-Lactone; NSC 101088

产品登记号

• CAS号: 5119-48-2

产品性质

• 外观: White Solid
• 熔点: 228-230°C
• 溶解度: Chloroform
• 溶解度: Methanol
• 保存条件: -20°C Freezer

产品详细信息

详细说明 (English)

Withaferin A is a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera. Withaferin A showed potent cytotoxicity against human head and neck squamous cell carcinoma (JMAR and MDA-1986).

参考文献

• Shohat, B., et al.: Cancer Chemother. Rep., 51, 271 (1967)
• Shohat, B., et al.: Int. J. Cancer., 8, 487 (1967)